HORDB

General Information

ID: hor000419
Uniprot ID: NA
Protein name: Allatostatin B
Gene name: NA
Organism: Cancer borealis
Family: Allatostatin family
Source: Animal
Expression: pericardial organs
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: TSWFKFQGSW
Length: 10
Propeptide: NA
Signal peptide: NA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Activity

Function: Act as neuromodulators but also as hormones
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
Kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000419_AF2.pdb

hor000419_ESM.pdb

Physical Information

Mass:	143411	Formula:	C63H80N14O15
Absent amino acids:	ACDEHILMNPRVY	Common amino acids:	FSW
pI:	9.7	Basic residues:	1
Polar residues:	4	Hydrophobic residues:	4
Hydrophobicity:	-63	Boman Index:	-890
Half-Life / Aliphatic Index:	7.2 hour	Aliphatic Index:	0
Instability Index:	-603	Extinction Coefficient cystines:	11000
Absorbance 280nm:	1222.22

Literature

PubMed ID: 18700782
Title: Combining Microdialysis, NanoLC-MS, and MALDI-TOF/TOF to Detect Neuropeptides Secreted in the Crab, Cancer Borealis